Public flashcard deck · 19 cards

Immunology Final 2012 questions - Answers

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1. Front

   Receptor found on both memory and effector Th and Tc cells:
   Back

   IL-2R
2. Front

   migration of B lymphocytes to specific sites (such as a lymph node) is dependent in part on the utilization of:
   Back

   selectins
3. Front

   the classical pathway of complement begins with:
   Back

   activation of C1
4. Front

   the constant region of the five major types of heavy chains of Ig molecules determine the molecule’s:
   Back

   isotype
5. Front

   antibodies (immunoglobulins):
   Back

   tag antigens for destruction and removal
6. Front

   A T cell signal 1 and no response:
   Back

   anergy
7. Front

   Self-tolerance is mediated with a following mechanism apart from:
   Back

   immunodeviation
8. Front

   In activated T cells, CD152 (CTLA4):
   Back

   begins to move to the membrane and bind CD80/86 (aka B7)
9. Front

   CD4+ T cells that respond to intracellular pathogens by recruiting and activating phagocytic cells are termed:
   Back

   Th1 cells
10. Front

    The Fab region of an antibody is responsible for
    Back

    binding to antigen
11. Front

    B-lymphocytes mature in the human body in the:
    Back

    bone marrow
12. Front

    Th2-type immune response is not characterized by:
    Back

    stimulation of CD8 T cells to kill virally infected cells
13. Front

    Which of the following sentences is true
    Back

    Ligation of TLR4 with bacteria (LPS) activates APC cells
14. Front

    Microbes can invade the host immune system by:
    Back

    all of the above
15. Front

    Secretory IgA protects external mucosal surface by:
    Back

    preventing microbial adherence to the mucosa
16. Front

    Which of the following cytokines can mediate release of acute phase proteins from the liver
    Back

    IL-1 and IL-6
17. Front

    Which of the following statements best describes the differences between recognition of antigen by T or B cells
    Back

    T-cells recognize foreign peptides in the context of self MHC molecules, while B cells recognize soluble antigens
18. Front

    Negative T cell selection in the thymus is based on:
    Back

    presentation of self antigens in the context of self MHC
19. Front

    Antibody titer refers to
    Back

    highest dilution of antibodies still able to give a positive result in a test system