Public flashcard deck · 30 cards

DDS Immuno Final 2024

Study this deck free Add to my library

1. Front

   The negative selection of a direct MACS analysis is dedicated for the selection of the following cell populations:
   Back

   NK cells and T lymphocytes
2. Front

   Affinity of released antibodies is increased by:
   Back

   somatic mutations of VDJ segments in immunoglobulin-encoding genes
3. Front

   Information about pathogenicity of an antigen is transmitted by:
   Back

   costimulatory molecules expressed by APCs after stimulation of TLRs
4. Front

   The main difference between classical immune response and hypersensitivity is that:
   Back

   the first contact with the allergen induces the sensitization phase, and the effecter phase is activated by repeated exposure to the same allergen
5. Front

   Complementary determining regions:
   Back

   are involved in antigen recognition
6. Front

   If a patient suffering from flu receives anti-flu vaccine, he or she may develop an adverse effect that results from:
   Back

   formation of immune complexes that drives cutaneous/muscular Arthurs reaction in type III hypersensitivity
7. Front

   Which of the following mediators are responsible for oxygen-dependent killing of pathogens by phagocytes?
   Back

   ROs, NO, hypochlorous acid
8. Front

   Which vaccines are most effective in inducing the cellular response?
   Back

   attenuated vaccines
9. Front

   Immunological facilitation is the mechanism of tolerance observed in:
   Back

   cancer cells which avoid the specific immune response against their cell surface antigens
10. Front

    Suppression of Th1 cells by Th2 cells may be mediated by:
    Back

    IL-10
11. Front

    Cross presentation of an antigen allows for:
    Back

    activation of CD8+ T cell by endocytosed antigen
12. Front

    An example of privileged immunological site is the:
    Back

    testis
13. Front

    Hemolytic disease of the newborn is caused by:
    Back

    cytotoxic and cytolytic elimination of fetal Rh(+) erythrocytes opsonized by incomplete IgG produced by B2 cells of the sensitized Rh(-) mother
14. Front

    Which of the following confers passive immunity?
    Back

    cross placental transfer of maternal antibodies
15. Front

    Very high serum titer in patient with bacterial infection in the agglutination test indicates:
    Back

    presence of anti-bacterial antibodies and secondary immune response
16. Front

    Which of the following is a primary lymphoid organ?
    Back

    Thymus
17. Front

    CD4 molecule, crucial for HIV infection, is expressed on:
    Back

    T helper cells and monocytes/macrophages
18. Front

    Which of the following are considered effector cells of the innate immunity?
    Back

    Natural Killer (NK) cells
19. Front

    Which class of immunoglobulins contains secretory component?
    Back

    IgA2
20. Front

    Which of the following cytokines can mediate release of acute phase protein from the liver?
    Back

    IL-6
21. Front

    The NBT (nitro blue tetrazolium) assay allows us to screen for the disturbances of:
    Back

    intracellular killing of pathogens by phagocytes
22. Front

    Mechanisms of autotolerance (self-tolerance) involve:
    Back

    clonal deletion, clonal anergy, active suppression and sequestration of antigens
23. Front

    Activation of complement is responsible for tissue damage in:
    Back

    immune complex-mediated hypersensitivity
24. Front

    The best method to define the phenotype (size, granularity, expression of particular CD markers) of immune cells is:
    Back

    flow cytometry
25. Front

    Production of self-reacting IgM antibodies supports:
    Back

    breaking of clonal anergy
26. Front

    Activation of Cd8+ T cells by weakly pathogenic antigen can be supported by:
    Back

    CD4+ helper type 1 T lymphocytes
27. Front

    In type I allergy reactions result from:
    Back

    binding of homologous epitopes from different allergens by the same IgE molecules
28. Front

    Metal braces, crowns, and dental fillings may include:
    Back

    delayed-type hypersensitivity
29. Front

    mRNA Covid-19 vaccines:
    Back

    can stimulate both humoral and cellular responses
30. Front

    Thymus-independent antigens:
    Back

    are usually polymeric antigens