Public flashcard deck · 32 cards

Immunology MD 2023 Final - Answers

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1. Front

   APCs are characterized by:
   Back

   Expression of MHC class II
2. Front

   Information about the pathogenicity of an antigen is transmitted
   Back

   Costimulatory molecules expressed by APCs after stimulation of TLRs
3. Front

   Which one of the following is an agent used to augment the effects of a vaccine
   Back

   Adjuvant
4. Front

   Which of the following diseases has been eradicated thanks to vaccination?
   Back

   Smallpox
5. Front

   The property of cytokine to have multiple biologic actions on different target cells is known as:
   Back

   Pleiotropism
6. Front

   The most efficient and fastest strategy of gaining herd immunity in COVID-19 is:
   Back

   Massive Vaccinations
7. Front

   In contrast to effector T cell, naive T lymphocyte fails to express:
   Back

   IL-2R
8. Front

   ADCC response of NK cells against virus-infected cell is induced by:
   Back

   IgG specifically bound to viral capside protein on plasma membrane of target cell
9. Front

   Mechanism of immune tolerance that is broken in atopic individuals is called:
   Back

   Immune ignorance
10. Front

    In the process of inflammation, the vasodilation is the result of:
    Back

    mast cell degranulation
11. Front

    Secretory IgA protects external mucosal surface by:
    Back

    Preventing microbial adherence to the mucosa
12. Front

    Mark the sentence that is True regarding cellular immune essays:
    Back

    Using MACS, you may sort T cells with negative selection, but positive selection is more common
13. Front

    Which one of the following sentences is not True
    Back

    Live attenuated vaccines can be safely used in immunodeficient individuals
14. Front

    Hapten binding the skin-derived self-protein induces:
    Back

    Contact hypersensitivity (contact dermatitis)
15. Front

    Degradation in proteasomes is characteristic for:
    Back

    Intrinsic antigens
16. Front

    Recombination of V, D and J immunoglobin gene segments:
    Back

    Is performed by recombinase enzymes RAG1 and RAG-2
17. Front

    The interaction between antibody and a particulate antigen resulting in visible clumping is called:
    Back

    Agglutination
18. Front

    Mark the sentence that is True in regards to allergic humoral reaction:
    Back

    Type I allergy is the only hypersensitivity mediated by IgE antibodies
19. Front

    Which of the following is not True:
    Back

    T cell receptors recognize conformational epitopes
20. Front

    Mechanism of autotolerance (self-tolerance) involve:
    Back

    Clonal deletion, clonal anergy, active suppression and sequestration of antigens
21. Front

    Which IgG immunoglobin subclass is not able to activate complement?
    Back

    IgG4
22. Front

    Type I interferon:
    Back

    Induces cytokine synthesis in NK cells
23. Front

    Which of the following is True about the innate immunity
    Back

    It recognizes pathogen-associated and damage-associated molecular patterns
24. Front

    Hemolytic disease of the newborn is caused by:
    Back

    Cytotoxic and cytolytic elimination of fetal Rh+ erythrocytes opsonized by incomplete IgG produced by B2 cells of the sensitized Rh- mother
25. Front

    Measured absorbance is directly proportional to the concentration of the antigen in:
    Back

    Indirect and sandwich ELISA
26. Front

    Which of the following mediators are responsible for oxygen-dependent killing of pathogens by phagocytes?
    Back

    ROIS, NO, hypochlorous acid
27. Front

    Secondary cytotoxic response of CD8+ T cells is activated by specific recognition of antigen presented by:
    Back

    MHC class I-expressing somatic cell
28. Front

    Which class of immunoglobins contains secretory component
    Back

    IgA2
29. Front

    In comparison with primary response, anamnestic response is Not characterized by:
    Back

    Longer lag phase
30. Front

    Which of the complement pathways is (are) strictly innate, requiring no direct input from the adaptive immune system:
    Back

    Both the alternative and the lectin pathways
31. Front

    The most common diagnostic assay for presence of maternal anti-Rh antibodies in serum is:
    Back

    Indirect coombs test
32. Front

    Treg lymphocytes support clonal anergy by:
    Back

    Binding of CD80/86 on APC with their CD152