Public flashcard deck · 30 cards

Immunology Final 2019 - Answers

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1. Front

   Which of the following cytokines can mediate release of acute phase protein?
   Back

   IL-6 + TNF-alpha
2. Front

   Virally infected cells can be killed directly by:
   Back

   NK cells
3. Front

   Which of the following molecules is expressed by both effector and memory TH1 cells and Tc cells?
   Back

   IL-2R
4. Front

   TH2-type immune response is NOT characterized by:
   Back

   Cytotoxic effect on the target cell
5. Front

   Which immunoglobulin class crosses placenta to provide a high level of passive immunity at birth:
   Back

   IgG
6. Front

   The adaptive immune system contributes to immune surveillance of the oral cavity by the secretion of:
   Back

   IgA
7. Front

   Dendritic cells (DC) present foreign antigen to T lymphocytes primarily in the:
   Back

   Lymph nodes
8. Front

   Self-tolerance is mediated with a following mechanisms except:
   Back

   Immune deviation
9. Front

   IgE antibody:
   Back

   Binds strongly to mast cells
10. Front

    In the type III allergic reaction (immune complexes) the first cells to appear at the site of reaction are:
    Back

    Neutrophils
11. Front

    Microbes can evade the host immune response by:
    Back

    All of the above
12. Front

    Protection against intracellular pathogens is provided by:
    Back

    T cells and NK cells
13. Front

    The major advantages of “killed” over “live attenuated” viral vaccines include:
    Back

    Vaccine can be given to immunodeficient patients
14. Front

    Which of the following is the best diagnostic test in evaluation of level of antibodies against bacteria in patient serum?
    Back

    ELISA
15. Front

    Which type of hypersensitivity is represented by contact dermatitis?
    Back

    Delayed type
16. Front

    A state of T lymphocytes unresponsiveness that occurs under certain circumstances following peptide + MHC engagement is known as:
    Back

    Anergy
17. Front

    Humoral response to T-dependent antigens is characterized by:
    Back

    Induction of antigen specific B cells in the presence of CD4+ T cells
18. Front

    TH2-type immune responses are characterized by all of the following EXCEPT:
    Back

    Stimulation of cytotoxic T cells to kill virally infected cells
19. Front

    Suppression of TH1 cells by TH2 cells may be mediated by:
    Back

    IL-10
20. Front

    MHC class II molecules are found on:
    Back

    B cells, APC cells and macrophages
21. Front

    Activation of complement is responsible for tissue damage in:
    Back

    Type III hypersensitivity
22. Front

    Antibodies:
    Back

    Tag antigens for destruction and removal
23. Front

    T cell receptor recognizes:
    Back

    Linear antigen peptide in the MHC groove
24. Front

    Which of the following sentences is false?
    Back

    The Rosette test was invented as a method to estimate the number of B lymphocytes
25. Front

    Prior to class switching, B-cells express:
    Back

    IgM and IgD
26. Front

    The Fab region of an antibody is responsible for:
    Back

    Binding of antigen epitopes
27. Front

    Antibody titer refers to:
    Back

    Highest dilution of antibodies still able to give a positive result in a test system
28. Front

    Purification of which of the following requires negative selection in MACS?
    Back

    Lymphocytes
29. Front

    Deliberate inactivation and destruction of lymphocytes bearing BCRs or TCRs capable of recognizing and binding specific self-epitopes results in:
    Back

    Self-tolerance
30. Front

    Immunological unresponsiveness to self-antigens is called:
    Back

    Tolerance