Public flashcard deck · 40 cards

MD Immuno Final 2024 - Answers

Study this deck free Add to my library

1. Front

   Degradation in proteasomes is a characteristic for?
   Back

   Intrinsic antigens
2. Front

   Which IgG immunoglobulin subclass is NOT ABLE to activate complement?
   Back

   IgG4
3. Front

   Hemolytic disease of the newborn is caused by:
   Back

   Cytotoxic and cytolytic elimination of fetal Rh(+) erythrocytes opsonized by incomplete IgG produced by B2 cells of the sensitized Rh(-) mother
4. Front

   Which class of immunoglobulins contains secretory component?
   Back

   IgA2
5. Front

   Receptor-dependent killing by cytotoxic lymphocytes involve interaction of:
   Back

   FasL-Fas, TNF-TNFR
6. Front

   Thymus-independent antigens:
   Back

   Are usually polymeric antigens
7. Front

   Secondary cytotoxic response of CD8+ T cells is activated by specific recognition of antigen presented by:
   Back

   MHC class I-expressing somatic cell
8. Front

   Hapten binding to skin-derived self-proteins induces:
   Back

   Contact hypersensitivity (contact dermatitis)
9. Front

   In competitive ELISA test concentrations of tested antigens are:
   Back

   Inversely proportional to absorbance
10. Front

    Which of the complement pathways is (are) strictly innate, requiring no direct input from the adaptive immune system?
    Back

    Both the alternative and the lectin pathways
11. Front

    Plasma cell differs from B cell in its ability to:
    Back

    Secrete immunoglobulins extracellularly
12. Front

    The crucial process of the central phase of primary humoral response leads to:
    Back

    Immunoglobulin class switching
13. Front

    If a patient suffering from flu receives anti-flu vaccine, he or she may develop an adverse effect that results from:
    Back

    Formation of immune complexes that drive cutaneous/muscular Arthurs reaction in type III hypersensitivity
14. Front

    In type III allergy, cytotoxic endothelial damage is caused by:
    Back

    Neutrophils attempting to phagocytize immune complexes deposited on the endothelium
15. Front

    Acute inflammation can be initiated by:
    Back

    Inflammasome activation
16. Front

    Which of the following statements regarding pattern recognition receptors (PRRs) is FALSE?
    Back

    PRRs express higher diversity of recognized molecules than TCRS
17. Front

    The following reagent is used in the indirect MACs procedure:
    Back

    Magnetic beads conjugated to the polyclonal Ig of the anti-gamma heavy chain of the host which is the producer of the monoclonal antibody used to recognize surface markers
18. Front

    IL-4 and IL-5 both inducing proliferation of B cells is an example of cytokine:
    Back

    Redundancy
19. Front

    Which vaccines were administered orally?
    Back

    Koprowski's and Sabin's vaccine
20. Front

    What is true regarding allergic humoral reactions?
    Back

    Type I allergy is the hypersensitivity mediated by IgE antibodies
21. Front

    The Acquired Immunodeficiency Syndrome (AIDS) is the consequence of the Human Immunodeficiency Virus (HIV) infection of the following immune target cells:
    Back

    Monocytes, macrophages, T helper lymphocytes
22. Front

    Cross-presentation of an antigen allows for:
    Back

    Activation of CD8+ T cell by endocytosed antigen
23. Front

    Mechanism of immune tolerance that is broken in atopic individuals is called:
    Back

    Immune ignorance
24. Front

    ADCC response of NK cells against virus-infected cell is induced by:
    Back

    IgG specifically bound to capsid protein on plasma membrane of target cell
25. Front

    Which vaccine is NOT an attenuated one?
    Back

    A pertussis vaccine
26. Front

    Adaptive immunity:
    Back

    Its mechanisms often depend on interaction with components of innate immunity
27. Front

    During Ficoll separation we can obtain lymphocytes and monocytes in one layer, how can we remove monocytes in the next step?
    Back

    By placing all cells on a plastic dish, monocytes will adhere by adding SRBC
28. Front

    Which class of immunoglobulins is produced by B1 lymphocytes?
    Back

    IgM
29. Front

    Which of the following DOES NOT contribute to antibody diversity?
    Back

    VDJ joining of the genes coding for the light chain of the antibody
30. Front

    Mechanisms of autotolerance (self-tolerance) involves:
    Back

    Clonal deletion, clonal anergy, active suppression, and sequestration of antigens
31. Front

    Which of the following activities are most closely associated with NK cells?
    Back

    Lysis of virus-infected or neoplastic cells
32. Front

    APCs are characterized by:
    Back

    Expression of MHC class II
33. Front

    Which of the following ARE NOT classified as extrinsic antigens?
    Back

    Viral peptides synthesized and presented by infected dendritic cell
34. Front

    Able to regulate inflammatory response
    Back

    All of the above
35. Front

    The main difference between classical immune responses and hypersensitivity reactions is that:
    Back

    The first contact with the allergen induces the sensitization phase, and the effector phase is activated by repeated exposure to the same antigen
36. Front

    Which vaccines are most effective in inducing the cellular response?
    Back

    Attenuated vaccines
37. Front

    Tuberculosis (BCG) vaccine is an example of:
    Back

    A monovalent vaccine
38. Front

    Complementarity determining regions:
    Back

    Are involved in antigen recognition
39. Front

    Which of the following are considered effector cells of the innate immunity?
    Back

    Natural Killer (NK) cells
40. Front

    What statement regarding adjuvants is FALSE?
    Back

    Aluminum salts are no longer used as adjuvants