KlappaNephritic Syndrome Pathology
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- FrontNephritic syndrome is characterized by which of the following?BackRBC casts and dysmorphic RBCs in urine
- FrontWhich of the following is most characteristic of nephritic syndrome?BackOliguria and azotemia
- FrontA patient with nephritic syndrome most commonly develops which of the following?BackSalt retention with periorbital edema and hypertension
- FrontRenal biopsy in nephritic syndrome most commonly shows which of the following?BackHypercellular, inflamed glomeruli
- FrontGlomerular injury in nephritic syndrome is primarily mediated by which of the following?BackImmune-complex deposition activating complement
- FrontWhich complement fragment attracts neutrophils in nephritic syndrome?BackC5a
- FrontA child develops cola-colored urine 2 weeks after streptococcal pharyngitis. Which diagnosis is most likely?BackPoststreptococcal glomerulonephritis
- FrontPoststreptococcal glomerulonephritis most commonly occurs after infection with which organism?BackGroup A beta-hemolytic streptococcus
- FrontPoststreptococcal glomerulonephritis typically presents how long after infection?Back2 to 3 weeks
- FrontWhich of the following is the classic urine appearance in poststreptococcal glomerulonephritis?BackCola-colored urine
- FrontWhich age group is most commonly affected by poststreptococcal glomerulonephritis?BackChildren
- FrontImmunofluorescence in poststreptococcal glomerulonephritis most commonly shows which pattern?BackGranular
- FrontElectron microscopy in poststreptococcal glomerulonephritis classically reveals which finding?BackSubepithelial humps
- FrontWhich of the following is the usual treatment for poststreptococcal glomerulonephritis?BackSupportive care
- FrontWhich of the following is a possible complication of poststreptococcal glomerulonephritis in adults?BackRapidly progressive glomerulonephritis
- FrontRapidly progressive glomerulonephritis is defined as nephritic syndrome that progresses to renal failure over what period?BackWeeks to months
- FrontWhich histologic finding is characteristic of rapidly progressive glomerulonephritis?BackCrescents in Bowman space
- FrontCrescents in rapidly progressive glomerulonephritis are composed primarily of which of the following?BackFibrin and macrophages
- FrontWhich immunofluorescence pattern is classically seen in Goodpasture syndrome?BackLinear
- FrontGoodpasture syndrome is caused by antibodies directed against which structure?BackType IV collagen in basement membranes
- FrontA young man with hematuria and hemoptysis most likely has which condition?BackGoodpasture syndrome
- FrontWhich of the following diseases is associated with pauci-immune rapidly progressive glomerulonephritis?BackWegener granulomatosis
- FrontWhich antibody is associated with Wegener granulomatosis?Backc-ANCA
- FrontWhich diseases are associated with p-ANCA?BackMicroscopic polyangiitis and Churg-Strauss syndrome
- FrontWhich of the following findings helps distinguish Churg-Strauss syndrome from microscopic polyangiitis?BackGranulomatous inflammation, eosinophilia, and asthma
- FrontIgA nephropathy is caused by deposition of which substance in the mesangium?BackIgA immune complexes
- FrontIgA nephropathy is the most common nephropathy in which setting?BackWorldwide
- FrontA child develops episodic hematuria after a respiratory infection. Which diagnosis is most likely?BackIgA nephropathy
- FrontWhich urine finding is commonly seen in IgA nephropathy?BackRBC casts
- FrontImmunofluorescence in IgA nephropathy most commonly shows deposition of which substance?BackIgA in mesangium
- FrontWhich of the following nephritic syndromes is most likely to slowly progress to renal failure?BackIgA nephropathy
- FrontWhich of the following is a hallmark clinical feature of nephritic syndrome but not nephrotic syndrome?BackHematuria with red cell casts
- FrontHypertension in nephritic syndrome is primarily due to which of the following?BackFluid retention and increased renin release
- FrontOliguria in nephritic syndrome results primarily from which of the following?BackReduced GFR
- FrontWhich of the following is most likely to produce a nephritic syndrome with diffuse proliferative glomerulonephritis?BackSystemic lupus erythematosus
- FrontWhich immunofluorescence pattern is most likely in diffuse proliferative glomerulonephritis due to lupus?BackGranular
- FrontWhich of the following nephritic conditions is associated with hemoptysis?BackGoodpasture syndrome
- FrontWhich type of rapidly progressive glomerulonephritis has negative immunofluorescence?BackPauci-immune RPGN
- FrontWhich of the following is most characteristic of anti-GBM disease on immunofluorescence?BackLinear IgG and C3 staining
- FrontWhich of the following findings is most characteristic of nephritic syndrome?BackHypercellular glomeruli with leukocyte infiltration
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