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Immunology Final 2022 questions - Answers

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1. Front

   Mechanism of immune tolerance that is broken in atopic individuals is called:
   Back

   immune ignorance
2. Front

   ADCC response of NK cells against virus-infected cell is induced by:
   Back

   IgG specifically bound to capside protein on plasma membrane of target cell
3. Front

   The following statements regarding innate immunity are true, EXCEPT:
   Back

   it relies on antibody formation and cell-mediated immunity to achieve its functions
4. Front

   Maturation of the B lymphocytes takes place in the:
   Back

   bone marrow
5. Front

   Which class of immunoglobulins contains secretory component?
   Back

   IgA2
6. Front

   The interaction between an antibody and a soluble antigen in aqueous solutions that forms a lattice (a net), which develops into a visible aggregate is called:
   Back

   precipitation
7. Front

   mRNA Covid-19 vaccines:
   Back

   can stimulate both humoral and cellular responses
8. Front

   Which of the following diseases has been eradicated by vaccination?
   Back

   smallpox
9. Front

   Which of the following is an agent used to augment the effects of a vaccine?
   Back

   adjuvant
10. Front

    Braces, crowns and dental fillings may induce:
    Back

    delayed-type hypersensitivity
11. Front

    The best method to define the phenotype (size, granularity, expression of particular CD markers) of immune cells is:
    Back

    flow cytometry
12. Front

    Which of the following is characteristic of acute inflammation?
    Back

    accumulation of PMNs (neutrophils)
13. Front

    Which of the following are NOT classified as extrinsic antigens?
    Back

    viral peptides synthetized and presented by infected dendritic cell
14. Front

    Delayed type Hypersensitivity disease is considered as:
    Back

    Type IV hypersensitivity
15. Front

    Treg lymphocytes support clonal anergy by:
    Back

    binding of CD80/86 on APC with their CD152
16. Front

    Which of the following best describes Type I hypersensitivity:
    Back

    immediate hypersensitivity which is caused by the release of mediators from mast cells triggered by antigen cross-linking immunoglobulin E bound to IgE receptors
17. Front

    Adherence of SARS-CoV-2 to the respiratory epithelium is blocked by:
    Back

    specific IgA antibodies
18. Front

    Which one of the following is a primary lymphoid organ:
    Back

    thymus
19. Front

    The following statements regarding periodontitis are true, EXCEPT:
    Back

    gingivitis and periodontitis is the same
20. Front

    Cytometric analysis allows us to:
    Back

    all answers are correct
21. Front

    Activation of CD8+ T cells by weakly pathogenic antigen can be supported by:
    Back

    CD4+ helper type 1 T lymphocytes
22. Front

    In contrast to primary humoral response, secondary response is characterized by:
    Back

    fast production of highly specific antibodies
23. Front

    T-independent antigens activate the secretion of immunoglobulins by:
    Back

    B1 lymphocytes
24. Front

    Gradient centrifugation is commonly used to separate immune cells according to the differences in:
    Back

    cellular density
25. Front

    Which of the following mediators are responsible for oxygen-dependent killing of pathogens by phagocytes?
    Back

    ROIs, NO, hypochloride acid
26. Front

    Mechanisms of autotolerance (self-tolerance) involve:
    Back

    clonal deletion, clonal anergy, active suppression and sequestration of antigens
27. Front

    Which of the following sentences regarding inactivated vaccines is NOT TRUE?
    Back

    they induce predominantly cellular response
28. Front

    Toll-Like Receptors (TLR):
    Back

    recognize Pathogen-Associated Molecular Patterns (PAMPs) on selective microorganisms
29. Front

    Which of the following processes fulfills the second condition of antigen presentation?
    Back

    interaction between adhesion and costimulatory molecules