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Immunology Final 2017 questions - Answers

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  1. Front
    Which cells are responsible for delayed type of hypersensitivity?
    Back
    Th1 cells and macrophages
  2. Front
    Self-tolerance is mediated with the following mechanisms except:
    Back
    Immune deviation (Induction of regulatory T-cell development instead of effector T-cell development)
  3. Front
    IgE antibody:
    Back
    Binds strongly to mast cells
  4. Front
    In the type III allergic reaction (immune complexes) the first cells to occur at the site of reaction are:
    Back
    Neutrophils
  5. Front
    Virally infected cells can be killed directly by:
    Back
    NK cells
  6. Front
    Which of the following molecules is expressed by both effector and memory Th1 and Tc cells?
    Back
    IL-2R
  7. Front
    Th2-type immune response is not characterized by:
    Back
    Cytotoxic effect on the target cell
  8. Front
    Immunologic memory is based on which of the following?
    Back
    Expanded populations of antigen-specific lymphocytes
  9. Front
    The adaptive immune system contributes to immune surveillance of the oral cavity by the secretion of:
    Back
    IgA
  10. Front
    Protection against intracellular pathogen is provided by:
    Back
    T cells and NK cells
  11. Front
    Suppression of Th1 cells by Th2 cells may be mediated by:
    Back
    IL-10
  12. Front
    Acute inflammatory response is characterized by:
    Back
    All of the above
  13. Front
    Antibodies
    Back
    Tag antigens for destruction and removal
  14. Front
    T cell receptor recognizes
    Back
    Linear antigen peptide in the MHC groove
  15. Front
    Which of the following sentences is true?
    Back
    Binding TLR4 with bacteria (LPS) activates APC cells
  16. Front
    The major advantages of ”killed” over ”live attenuated” viral vaccines include
    Back
    Vaccine can be given to immunodeficient patients
  17. Front
    Which type of hypersensitivity reaction is represented by atopic dermatitis?
    Back
    Immediate type – IgE dependent
  18. Front
    Which of the following cytokines can mediated release of acute phase proteins from the liver:
    Back
    IL-1 and IL-6
  19. Front
    Humoral response to T-dependent antigens is characterized by:
    Back
    Induction of antigen specific B cells and CD4+ T cells
  20. Front
    Radial immunodiffusion may be used for:
    Back
    Quantitative measurement of antigen or antibody
  21. Front
    Which molecules do not participate in acute inflammation:
    Back
    Antibodies
  22. Front
    Which method is the most accurate to diagnose presence of incomplete IgG anti-D (Rh) in human serum?
    Back
    Indirect Coombs test
  23. Front
    Secretory IgA protects external mucosal surface by
    Back
    Preventing microbial adherence to mucosa
  24. Front
    B-lymphocytes mature in the human body in the
    Back
    Bone marrow

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